Pathology of the breast

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Pathological examination has been the gold standard for diagnosis in cancer and its role has also included the elucidation of etiology, pathogenesis, clinicopathological correlation, and prognostication. The advent of newer technologies and the realization that breast cancer is heterogeneous has shifted the focus to prognostication, with increased attention being paid to the identification of morphological features and immunohistochemical markers of prognostic relevance. These 3 markers were initially employed for prognostication but their role in treatment also rendered them of predictive value.

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Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Breastsecond edition, is a visually stunning, easy-to-use reference covering all aspects of breast pathology. Outstanding images, including gross and microscopic pathology, a wide range of supportive immunohistochemistry, and detailed medical illustrations with numerous examples of morphologic findings, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. David Hicks is a senior faculty member at the U of Rochester and has contributed to and authored Elsevier texts.

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Ensuring the accuracy of your pathology results is of utmost importance. Knowing the exact type of breast cancer and the specifics of its prognostic factors is critical to creating a treatment plan that will provide you with the best opportunity for defeating this disease. Our team of breast specialists includes pathology faculty members who specialize in breast cancer and have extensive experience evaluating and accurately classifying breast tissue specimens.

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Kimberly H. In the last decade and a half, molecular information has transformed our thinking about the biologic diversity of breast cancers and redirected the way clinical treatment decisions are made. A basic understanding of the current molecular classification of breast cancers and the biologic pathways from precursors to invasive disease is key to both informing diagnostic practice and serving as clinical consultants.

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This guide for pathologists, surgeons, radiologists and oncologists has been updated to reflect the latest evidence and consensus opinion in relation to the handling, examination and reporting of invasive carcinoma and ductal carcinoma in situ DCIS. Includes updated versions of synoptic reports for invasive carcinoma and DCIS. This resource was developed, reviewed or revised more than 5 years ago and may no longer reflect current evidence or best practice.

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The Breast Pathology Service provides comprehensive expertise for the diagnosis and evaluation of breast diseases. The Breast Service also provides national and international consultations for difficult and challenging breast diseases with diagnoses provided by a team of internationally recognized, highly experienced breast pathologists. Available resources for diagnosis include breast pathology experts with over 90 years of combined experience between them, access to an unparalleled range of immunohistochemical studies, and prognostic fluorescence in situ hybridization for HER2.

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Histopathology - Reviews and Recent Advances. Histopathology plays an important role in management of breast diseases. It is a necessary component of diagnosis, treatment and prognosis in most breast disorders.

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The expertise of our subspecialty-trained breast pathologists is widely sought by pathologists, clinicians, and patients requesting an expert opinion in breast pathology from a service with a great depth and breadth of experience and volume. We offer our clients the speed and accuracy of results that can make a life-saving difference. In addition to clinical services, our pathologists conduct research, develop new tests, and publish widely in the field.

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By Bill Piersol Tuesday, November 14, Edi Brogi says the best time to get a second opinion is soon after breast cancer is diagnosed, before definitive treatment begins. A breast cancer diagnosis often starts when a change is found during a breast exam or mammogram.


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